Last Holiday month, we drove from San Francisco to Phoenix to see family. This would normally take us about 12 hours. But with pets, it took us about 15+ hours. This included frequent stops for feeding, cleaning, walking and breathing. It gets stuffy quickly, especially inside a compact car. I'd feel sad boarding the pets at a hotel for 2 weeks.
That and my cats will end up resenting me if I leave them for that long. Last time I left them for a few days, they left pretty nasty "presents" on my bed. Eep.